Promethazine HCl and codeine phosphate oral Option is indicated for your short-term aid of coughs and upper respiratory signs related with allergy or the typical cold in patients eighteen years of age and more mature.
Neonatal Opioid Withdrawal Syndrome: Prolonged use throughout pregnancy may result in neonatal opioid withdrawal syndrome, which may be lifestyle-threatening if not identified and dealt with, and necessitates management In line with protocols made by neonatology experts.
Prescription drug abuse is the intentional non-therapeutic usage of a prescription drug, even once, for its rewarding psychological or physiological results.
Hypotension Notify sufferers that promethazine HCl and codeine phosphate oral Resolution may possibly lead to orthostatic hypotension and syncope. Instruct sufferers how to recognize signs of very low blood pressure and how to lessen the risk of severe implications ought to hypotension happen (e.
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Evaluate Each individual client's chance before prescribing and observe all sufferers frequently for the development of those behaviors or ailments.
Young children Postmarketing situations of respiratory melancholy, together with fatalities, have been reported with utilization of promethazine in pediatric patients. Concomitant administration with other respiratory depressants may well boost the chance of respiratory depression.
Constipation Consider to get far more fibre into your eating plan, which include fresh fruit, greens and cereals. Attempt to drink a number of Eyeglasses of drinking water or other non-alcoholic liquid every day. If you're able to, it may aid to carry out some gentle exercise.
In case the reaction to an opioid antagonist is suboptimal or only short in mother nature, administer extra antagonist as directed with the products’s prescribing information. The respiratory depressant effects of promethazine are certainly not reversed by opioid antagonists, which include naloxone.
are here breastfeeding or want to breastfeed. Codeine passes into your breast milk and could cause significant Uncomfortable side effects inside your toddler such as enhanced sleepiness, respiratory challenges (respiratory depression), and Dying. It is not known if promethazine can go into your breast milk.
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The estimated history hazard of important start defects and miscarriage to the indicated population is unknown. All pregnancies Have got a qualifications danger of start defect, reduction, or other adverse outcomes.
Use caution when considering the use of promethazine HCl and codeine phosphate oral Option in people sixty five yrs of age or older.
Life-Threatening Respiratory Despair Advise clients of the potential risk of daily life-threatening respiratory depression, together with data that the risk is biggest when commencing promethazine HCl and codeine phosphate oral Resolution and that it could possibly take place even at recommended dosages [see Warnings and Safeguards (five.